Department of Urology, Mayo Clinic, Rochester, Minnesota 55905, USA.
J Urol. 2011 Dec;186(6):2280-4. doi: 10.1016/j.juro.2011.07.103. Epub 2011 Oct 20.
Due to imaging limitations little is known about the true rate of spontaneous stone passage during pregnancy. We evaluated the accuracy of urolithiasis diagnosis during pregnancy and the rate of spontaneous passage.
We retrospectively reviewed the records of patients diagnosed with urolithiasis during pregnancy from 1997 to 2009. Patients were evaluated for a confirmed stone event, defined as a stone visualized on imaging or at surgery, or passed with visualization.
We identified 112 women diagnosed with urolithiasis during pregnancy, including 5 with multiple episodes for a total of 117 events. Stones were visualized by imaging in 63 of 117 events. Another 22 patients without imaging confirmation passed a stone spontaneously. In 1 patient the stone was diagnosed at surgical removal during pregnancy and postpartum imaging identified another 4 patients. Thus, 90 of 117 events (77%) represented confirmed stones. Of the 90 patients 27 (30%) underwent temporizing or definitive surgical intervention during pregnancy. Postpartum definitive surgical management was necessary in 29 women (25%). Overall only 43 of 90 women (48%) spontaneously passed the stone. Mean followup of those with confirmed stones was 51 months. Urolithiasis recurred in 26 of the 90 patients (29%). The most common primary component of analyzed stones was calcium phosphate (81%).
We found that almost a quarter of pregnant women diagnosed with urolithiasis are diagnosed inaccurately. The inappropriate diagnosis of urolithiasis may contribute to the misconception that most stones pass with conservative management during pregnancy.
由于影像学的限制,对于妊娠期间结石自然排出的真实发生率知之甚少。我们评估了妊娠期间尿路结石诊断的准确性和自然排出率。
我们回顾性分析了 1997 年至 2009 年期间被诊断为妊娠期间尿路结石的患者的记录。对有确诊结石事件的患者进行评估,定义为影像学或手术中发现结石,或经影像学证实排出结石。
我们共发现 112 例妊娠期间诊断为尿路结石的患者,其中 5 例有多次发作,共 117 例。63 例 117 例中有影像学证实的结石。另外 22 例未行影像学证实的患者自发排出结石。1 例患者在妊娠期间手术切除时诊断为结石,产后影像学检查又发现了另外 4 例患者。因此,117 例中有 90 例(77%)为确诊结石。90 例患者中,27 例(30%)在妊娠期间接受了临时或确定性手术干预。29 例患者(25%)在产后需要确定性手术治疗。总的来说,90 例患者中只有 43 例(48%)自发排出结石。对有确诊结石的患者的平均随访时间为 51 个月。90 例患者中有 26 例(29%)结石复发。分析结石的主要成分最常见的是磷酸钙(81%)。
我们发现,近四分之一被诊断为尿路结石的孕妇诊断不准确。尿路结石的误诊可能导致人们错误地认为大多数结石在妊娠期间采用保守治疗可以自行排出。