Anhui Provincial Key Laboratory of Population Health and Aristogenics, Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, 81 Meishan Road, Hefei 230032, China.
Midwifery. 2012 Jun;28(3):291-7. doi: 10.1016/j.midw.2011.04.002. Epub 2011 Oct 19.
to examine the rate of periconceptional and optimal folic acid supplementation, and to characterise their patterns and determinants among antenatal women in central China.
data from 4290 women in the Anhui Birth Defects and Child Development Cohort Study recruited between October 2008 and September 2009 were analysed.
seven Maternal and Child Health Centres of two cities (Hefei and Maanshan) in Anhui province of central China.
women initiating prenatal care were included and asked to complete a structured questionnaire regarding folic acid supplementation.
sixty-eight per cent (2905/4290) of pregnant women reported taking folic acid supplementation periconceptionally (i.e. at some point before or during early pregnancy), and 32.8% (1405/4290) and 65.2% (2797/4290) had taken it before or during early pregnancy, respectively. However, only 16.1% (690/4290) used it optimally (i.e. regularly from four weeks before pregnancy throughout four weeks after pregnancy). Use of periconceptional folic acid was significantly associated with educational level, household income, registered residence, age, gestational age at recruitment, and planning of pregnancy.
optimal folic acid supplementation was relatively low.
further efforts are needed to inform the population and promote the use of folic acid supplementation.
研究围孕期和最佳叶酸补充的比例，并分析中国中部地区产前妇女补充叶酸的模式和决定因素。
分析了 2008 年 10 月至 2009 年 9 月期间在中国中部安徽省出生缺陷和儿童发展队列研究中招募的 4290 名女性的数据。
安徽省合肥市和马鞍山市的 7 个妇幼保健中心。
纳入了开始产前保健的女性，并要求她们填写一份关于叶酸补充的结构化问卷。
68%（2905/4290）的孕妇报告围孕期（即在怀孕前或怀孕早期的某个时候）服用叶酸补充剂，32.8%（1405/4290）和 65.2%（2797/4290）分别在怀孕前或怀孕早期服用叶酸。然而，只有 16.1%（690/4290）的人最佳地（即从怀孕前四周开始并持续到怀孕后四周）使用叶酸。围孕期叶酸的使用与教育程度、家庭收入、登记居住地、年龄、招募时的孕龄以及妊娠计划显著相关。
最佳叶酸补充相对较低。
需要进一步努力告知人群并促进叶酸补充的使用。
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