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2013-2017 年北京市产前多种微量营养素补充剂使用的人口统计学差异和时间趋势。

Demographic variations and temporal trends in prenatal use of multiple micronutrient supplements in Beijing, 2013-2017.

机构信息

Institute of Reproductive and Child Health, National Health Commission Key Laboratory of Reproductive Health, Peking University Health Science Centre, Beijing, China.

Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Centre, Beijing, China.

出版信息

Public Health Nutr. 2021 Apr;24(5):826-833. doi: 10.1017/S1368980020004905. Epub 2020 Dec 2.

Abstract

OBJECTIVE

To provide updated information about demographic variations and temporal trends in the prenatal use of multiple micronutrient (MMN) supplements in the metropolitan areas of China.

DESIGN

Descriptive analysis of routine prenatal healthcare data between 2013 and 2017.

SETTING

Chaoyang District, Beijing, China.

PARTICIPANTS

A total of 197 346 pregnant women who attended their first prenatal care visit and provided information about MMN supplementation during the periconceptional period.

RESULTS

Of these pregnant women, 60·6 % reported consuming prenatal MMN supplements. In multivariate-adjusted models, there were significant gradients of age, education and parity in prenatal MMN supplementation, with the highest likelihood of MMN use among the oldest, the most highly educated and nulliparous women (Pfor trend < 0·001). Compared with that among unemployed women, prenatal MMN supplementation was more common among the employed, especially those engaged in business (adjusted relative risks (95 % CI): 1·08 (1·06, 1·10)) and management (1·10 (1·08, 1·12)). The proportion of prenatal MMN supplementation was 57·0 % in 2013, which increased to 63·5 % in 2017 (Pfor trend < 0·001). The trends varied by age, education and parity (Pfor heterogeneity < 0·001), whereas no significant difference was observed in trends across subgroups of ethnicity or occupation. The greatest magnitude increase in MMN supplement use occurred in women of age < 25 years (annual percent change: 5·7 %), less than high school education (9·6 %), parity ≥ 2 (6·8 %) or unemployment (6·1 %).

CONCLUSION

Approximately two-thirds of women consumed prenatal MMN supplements during the periconceptional period in the central area of Beijing and the proportion increased over time, indicating a need to evaluate the effectiveness and safety and to develop a guideline for relatively well-nourished women.

摘要

目的

提供中国大都市地区围孕期多种微量营养素(MMN)补充剂使用的人口统计学变化和时间趋势的最新信息。

设计

2013 年至 2017 年常规围产保健数据的描述性分析。

地点

中国北京市朝阳区。

参与者

共有 197346 名孕妇参加了第一次产前检查,并在围孕期提供了 MMN 补充剂使用信息。

结果

在这些孕妇中,60.6%报告服用了产前 MMN 补充剂。在多变量调整模型中,产前 MMN 补充剂的使用存在年龄、教育和产次的显著梯度,最年长、受教育程度最高和初产妇使用 MMN 的可能性最高(P 趋势<0.001)。与失业女性相比,在职女性,尤其是从事商业(调整后的相对风险(95%CI):1.08(1.06,1.10))和管理(1.10(1.08,1.12))的女性更常使用产前 MMN 补充剂。2013 年产前 MMN 补充剂的比例为 57.0%,2017 年增加到 63.5%(P 趋势<0.001)。趋势因年龄、教育和产次而异(P 异质性<0.001),但在种族或职业亚组中未观察到趋势差异。MMN 补充剂使用量增加最大的是年龄<25 岁的女性(年百分比变化:5.7%)、未接受过高中教育(9.6%)、产次≥2(6.8%)或失业(6.1%)。

结论

北京中心区约有三分之二的女性在围孕期服用了产前 MMN 补充剂,而且这一比例随着时间的推移而增加,这表明需要评估其有效性和安全性,并为营养状况相对较好的女性制定指南。

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