Malhotra N, Rani N, Rana K, Malhotra R K
Department of Biosciences, Himachal Pradesh University, Shimla, India.
Exp Pathol. 1990;38(4):241-8. doi: 10.1016/s0232-1513(11)80235-5.
White leghorn male chicks at 15 days post-hatching were subjected to acute (2.10 Gy and 6.60 Gy) and fractionated (2 x 2.10 Gy) whole body gamma radiation exposure at the high dose rate of 0.60 Gy/sec to study the nature of haematological changes induced in the animals which were maintained for a maximum period of 60 days post irradiation. The investigated parameters include total red blood cell counts, haemoglobin content, haematocrit value, mean corpuscular volume and mean corpuscular haemoglobin concentration values. The results show that the haematological changes induced with 2.10 Gy and 2 x 2.10 Gy fractionated dosage are reversible and do not cause permanent damage to the erythroid characteristics. However, the system failed to recover with 6.60 Gy whole body acute exposure.
孵化后15天的白来航雄性雏鸡接受急性（2.10 Gy和6.60 Gy）和分次（2×2.10 Gy）全身γ射线照射，剂量率为0.60 Gy/秒，以研究照射后维持60天的动物体内诱导的血液学变化的性质。研究参数包括总红细胞计数、血红蛋白含量、血细胞比容值、平均红细胞体积和平均红细胞血红蛋白浓度值。结果表明，2.10 Gy和2×2.10 Gy分次剂量诱导的血液学变化是可逆的，不会对红细胞特征造成永久性损伤。然而，6.60 Gy全身急性照射后该系统未能恢复。
