Department of Physical Therapy, Yeungnam College of Science and Technology, Taegu, Republic of Korea.
Neuroradiology. 2012 Jul;54(7):691-7. doi: 10.1007/s00234-011-0972-x. Epub 2011 Oct 21.
Predictability of diffusion tensor imaging tractography (DTT) for motor outcome can differ according to the time of DTT. We attempted to compare the predictability for motor outcome according to the time of diffusion tensor imaging (DTI) by analyzing the corticospinal tract (CST) integrity on DTT in patients with corona radiata (CR) infarct.
Seventy-one consecutive hemiparetic patients with CR infarct were recruited. Motor function of the affected extremities was measured twice: at onset and at 6 months from onset. According to the time of DTI, patients were classified into two groups: the early scanning group (ES group) within 14 days since stroke onset; and the late scanning group (LS group) 15-28 days. Motor outcome was compared with the CST integrity on DTT.
Motor prognosis was predicted from scan time of DTI and the CST integrity on DTT in the logistic regression model. According to separate regression analysis, the CST integrity of the late group was found to predict MI score (OR = 14.000, 95% CI = 3.194-61.362, p < 0.05), whereas the CST integrity of the early group was not found to predict MI score.
In terms of both positive and negative predictabilities, we found that predictability of DTT for motor outcome was better in patients who were scanned later (15-28 days after onset) than in patients who were scanned earlier (1-14 days after onset).
根据弥散张量成像（DTI）的时间，弥散张量成像追踪术（DTT）对运动预后的预测能力可能不同。我们试图通过分析皮质脊髓束（CST）在冠状辐射（CR）梗死患者的 DTT 中的完整性，比较根据 DTI 时间对运动预后的预测能力。
共纳入 71 例连续的 CR 梗死偏瘫患者。分别在发病时和发病后 6 个月测量患侧肢体的运动功能两次。根据 DTI 的时间，患者分为两组：发病后 14 天内的早期扫描组（ES 组）；和发病后 15-28 天的晚期扫描组（LS 组）。将运动预后与 DTT 上 CST 完整性进行比较。
逻辑回归模型显示，DTI 的扫描时间和 DTT 上 CST 的完整性可以预测运动预后。根据单独的回归分析，晚期组的 CST 完整性可以预测 MI 评分（OR=14.000，95%CI=3.194-61.362，p<0.05），而早期组的 CST 完整性不能预测 MI 评分。
无论是阳性还是阴性预测能力，我们发现，在发病后（发病后 15-28 天）扫描的患者中，DTT 对运动预后的预测能力比发病后（发病后 1-14 天）扫描的患者更好。
