Department of Physiology, RWTH Aachen University, Aachen, Germany.
Cytometry A. 2011 Nov;79(11):946-51. doi: 10.1002/cyto.a.21126. Epub 2011 Aug 30.
Elongation measurements of red cells subjected to simple shear flow are usually performed using a single suspending medium (viscosity η(0) ) and varying the mean shear rate (y). Such data are often plotted versus the shear stress (tau = no(y) suggesting that the elongation scales with τ. In this work, normal blood samples were tested in a rheoscope varying both η(0) and(y.). The ranges of (y.) were chosen to restrict the elongation of the red cells to low values where the behavior is dominated by their intrinsic properties. It was found that the elongation scales with η(0)(s)γ with s decreasing from two at η(0) = 20 mPas to unity at η(0) = 70 mPas. Above η(0) = 70 mPas, the elongation is therefore essentially determined by the membrane elasticity alone. A side observation was a large variation of the elongation both intraindividually and interindividually.
在单重悬浮介质（黏度 η(0)）中通过改变平均切变率（y）来测量红细胞在单纯切变流中的伸长率。此类数据通常绘制为剪切应力（tau = no(y)）的函数，表明伸长率与 tau 成正比。在这项工作中，通过流变仪改变 η(0)和(y.)来测试正常血样。选择(y.)的范围是为了将红细胞的伸长限制在低值范围内，在此范围内，红细胞的行为主要由其固有特性决定。研究发现，伸长率与 η(0)(s)γ 成正比，其中 s 在 η(0) = 20 mPas 时为 2，在 η(0) = 70 mPas 时为 1。在 η(0) > 70 mPas 时，伸长率仅由膜弹性决定。一个附带的观察结果是，红细胞的伸长率在个体内和个体间都有很大的变化。
