From the Women's and Children's Program Southern Health, Monash Medical Centre, Clayton, Victoria, Australia; the Department of Obstetrics and Gynaecology, University of Melbourne, Mercy Hospital for Women, Heidelberg, Victoria, Australia; and Teule Hospital, Muheza, Tanga Region, Tanzania.
Obstet Gynecol. 2011 Nov;118(5):995-999. doi: 10.1097/AOG.0b013e3182324570.
To characterize the symptoms that immediately precede eclamptic seizures.
We did a prospective observational study of all women admitted to a single center in Tanzania between May 1, 2007 and April 30, 2008 who had an eclamptic seizure. During their admission they were asked a uniform set of questions related to symptoms preceding the seizure.
There were 3,267 deliveries and 46 cases of eclampsia (1.4%). Neurologic symptoms (headache [80%] with or without visual disturbance [45%]) were the most common prodrome symptoms, regardless of degree of hypertension or whether the seizure occurred antepartum or postpartum. Twenty percent of women with eclampsia reported no neurologic symptoms before seizure.
Neurologic symptoms commonly precede eclampsia. A minority of patients with eclampsia (17%) had no prodromal symptoms before their eclamptic seizure. Premonitory symptoms may provide an early warning of imminent eclampsia.
描述子痫发作前的症状特征。
我们对 2007 年 5 月 1 日至 2008 年 4 月 30 日期间在坦桑尼亚的一家中心医院入院的所有子痫发作患者进行了前瞻性观察性研究。在住院期间，她们被问到与发作前症状相关的一组统一问题。
共有 3267 例分娩，46 例发生子痫（1.4%）。无论高血压程度如何，以及癫痫发作是在产前还是产后发生，神经系统症状（头痛[80%]，伴有或不伴有视觉障碍[45%]）是最常见的前驱症状。20%的子痫患者在癫痫发作前没有神经系统症状。
神经系统症状通常先于子痫。少数子痫患者（17%）在癫痫发作前没有前驱症状。前驱症状可能为即将发生的子痫提供早期预警。
