真菌组蛋白基因中暂定移动内含子的提取。
Extraction of tentative mobile introns in fungal histone genes.
作者信息
Nishida Hiromi, Yun Choong-Soo
机构信息
Agricultural Bioinformatics Research Unit; Graduate School of Agricultural and Life Sciences; University of Tokyo; Tokyo, Japan.
出版信息
Mob Genet Elements. 2011 May;1(1):78-79. doi: 10.4161/mge.1.1.15431.
We have identified 305 introns in fungal histone genes. Among the 305 introns, 21 had sequence similarities to introns that have different insertion sites. These 21 introns formed 13 intron-pairs. Nine of the 13 pairs had low similarities (35.3%-47.4%) between the flanking DNA sequences of the introns, suggesting that intron-homing or homologous recombination was rare event in the histone intron distribution. Six of the nine pairs consisted of the introns in the genes encoding the different histone families. On the other hand, four of the 13 pairs had 59.6-76.9% similarities between the flanking DNA sequences and the two intron sizes are similar. These four pairs consisted of the introns in the genes encoding the same histone family. Thus, in this analysis, intron-homings were not detected between the fungal genes encoding different histone families.
我们在真菌组蛋白基因中鉴定出了305个内含子。在这305个内含子中，有21个与具有不同插入位点的内含子存在序列相似性。这21个内含子形成了13个内含子对。13个对中的9个在内含子侧翼DNA序列之间具有较低的相似性（35.3%-47.4%），这表明内含子归巢或同源重组在组蛋白内含子分布中是罕见事件。9个对中的6个由编码不同组蛋白家族的基因中的内含子组成。另一方面，13个对中的4个在侧翼DNA序列之间具有59.6-76.9%的相似性，并且两个内含子大小相似。这4个对由编码相同组蛋白家族的基因中的内含子组成。因此，在该分析中，未在编码不同组蛋白家族的真菌基因之间检测到内含子归巢。
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