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精神科门诊患者中边缘型人格障碍与其他人格障碍的共病情况:2年随访时情况如何?

Comorbidity of borderline personality disorder with other personality disorders in psychiatric outpatients: how does it look at 2-year follow-up?

作者信息

Nysæter Tor E, Nordahl Hans M

机构信息

Department of Psychiatry, Sørlandet Hospital HF, Arendal, Norway.

出版信息

Nord J Psychiatry. 2012 Jun;66(3):209-14. doi: 10.3109/08039488.2011.621976. Epub 2011 Oct 24.

Abstract

BACKGROUND

The rates of remission of comorbid personality disorders for patients with a primary borderline personality disorder (BPD) have previously only been addressed in samples of inpatients or former inpatients with BPD receiving treatment-as-usual.

AIMS

The aim of the current study was to assess the rates of remission of comorbid axis II personality disorders in a sample of 32 outpatients with a primary BPD receiving open-ended non-manualized psychotherapy.

METHODS

Structured psychiatric interviews for DSM-IV were conducted by independent assessors at intake, discharge and 2-year follow-up. Independent t-test, chi-square and McNemar analyses based on intent-to-treat were used.

RESULTS

The overall rate of comorbid axis II disorders was significantly reduced from intake to 2-year follow-up. Patients with non-remitted BPD had significantly more PD diagnoses and symptomatic distress on all outcome measures at follow-up.

CONCLUSION

Comorbid personality disorders among outpatients with BPD can be expected to remit with time and with remission of BPD. In the current sample of outpatients, comorbid paranoid, avoidant and obsessive-compulsive personality disorders at 2-year follow-up were associated with non-remitted BPD. The clinical implication of the results is that especially comorbid avoidant and obsessive-compulsive personality disorders may require specific attention in treatment of patients with BPD.

摘要

背景

先前仅在接受常规治疗的住院或曾经住院的原发性边缘型人格障碍(BPD)患者样本中探讨过共病性人格障碍的缓解率。

目的

本研究旨在评估32例接受开放式非标准化心理治疗的原发性BPD门诊患者样本中共病的轴II人格障碍的缓解率。

方法

由独立评估者在入组、出院时及2年随访时进行DSM-IV结构化精神科访谈。采用基于意向性治疗的独立t检验、卡方检验和McNemar分析。

结果

从入组到2年随访,共病的轴II障碍总体发生率显著降低。未缓解的BPD患者在随访时所有结局指标上的人格障碍诊断和症状困扰显著更多。

结论

预计BPD门诊患者的共病性人格障碍会随时间推移以及BPD的缓解而缓解。在当前门诊患者样本中,2年随访时共病的偏执型、回避型和强迫型人格障碍与未缓解的BPD相关。结果的临床意义在于,在BPD患者的治疗中,尤其是共病的回避型和强迫型人格障碍可能需要特别关注。

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