Van Vynckt D, Samoy Y, Polis I, Bosmans T, Verschooten F, Van Ryssen B
Faculty of Veterinary Medicine, Department of Medical Imaging and Small Animal Orthopedics, Ghent University, Merelbeke 9820, Belgium.
J Small Anim Pract. 2011 Dec;52(12):638-44. doi: 10.1111/j.1748-5827.2011.01136.x. Epub 2011 Oct 22.
To assess the influence of two sedation protocols on the degree of lameness in dogs.
Fifty lame dogs were allocated to one of two sedation protocols. Group ACPM (acepromazine + methadone; n=25) was sedated with acepromazine and methadone. Group MED (medetomidine antagonised with atipamezole; n=25) was sedated with medetomidine and reversed with atipamezole. Each dog was evaluated for lameness before and after sedation using videotapes. Four experienced clinicians allocated global lameness scores before and after sedation to each dog using a numerical rating scale.
In 80% of the dogs in group ACPM and in 72% in group MED lameness was not affected by the sedation. In 12% of the dogs in group ACPM and 20% of the dogs in group MED the observers noticed an increase of lameness of 1 or 2 degrees on a scale of 0 to 10. In 8% of the dogs in both groups lameness decreased with 1 degree.
A possible diagnostic test for investigation of obscure lameness is intra-articular anaesthesia. Sedation is necessary to allow intra-articular injection. This study provided evidence that the effect of sedation with the proposed protocols on the degree of lameness is negligible.
评估两种镇静方案对犬跛行程度的影响。
将50只跛行犬分配至两种镇静方案之一。ACPM组(乙酰丙嗪+美沙酮;n=25)用乙酰丙嗪和美沙酮进行镇静。MED组(用阿替美唑拮抗的美托咪定;n=25)用美托咪定进行镇静并用阿替美唑进行逆转。使用录像带在镇静前后对每只犬的跛行情况进行评估。四名经验丰富的临床医生使用数字评分量表在镇静前后为每只犬分配整体跛行评分。
ACPM组80%的犬和MED组72%的犬的跛行未受镇静影响。ACPM组12%的犬和MED组20%的犬,观察者注意到在0至10分的量表上跛行增加了1或2度。两组中8%的犬跛行程度下降了1度。
关节内麻醉是一种用于检查隐匿性跛行的可能诊断测试。进行关节内注射需要镇静。本研究提供的证据表明所提议方案的镇静对跛行程度的影响可忽略不计。