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一例罕见的肝肉瘤样癌病例。

An unusual case of hepatic carcinosarcoma.

作者信息

Lai Q, Levi Sandri G B, Melandro F, Di Laudo M, Garofalo M, Guglielmo N, Grieco M, Di Tondo U, Rossi M, Berloco P B

机构信息

Department of General Surgery and Organ Transplantation, Sapienza University of Rome, Italy.

出版信息

G Chir. 2011 Aug-Sep;32(8-9):372-3.

Abstract

We report a rare case of a hepatic carcinosarcoma with rabdomyosarcomatous differentiation in its sarcomatous component. A 71-year old Caucasian female patient underwent a liver resection for a 4-cm lesion developed on an underlying HCV-related cirrhosis. Post-operative course was uneventful and the patient was discharged 5 days after surgery. At pathology, the tumor presented the features of hepatocellular carcinoma and rhabdomyosarcoma Three months later the patient experienced a liver recurrence, dying 2 months later for systemic disease. The reported case presents several peculiarities, i.e. the female gender, the HCV-related cirrhotic status, and the European origin of the patient. However, the outcome of our case confirms that this neoplasm pursues a highly aggressive course with poor prognosis.

摘要

我们报告了一例罕见的肝肉瘤样癌,其肉瘤成分具有横纹肌肉瘤分化。一名71岁的白种女性患者因潜在的丙型肝炎病毒(HCV)相关肝硬化上出现的4厘米病变接受了肝切除术。术后过程顺利,患者在手术后5天出院。病理检查显示,肿瘤具有肝细胞癌和横纹肌肉瘤的特征。三个月后,患者出现肝复发,两个月后因全身性疾病死亡。报告的病例具有几个特点,即女性性别、HCV相关的肝硬化状态以及患者的欧洲血统。然而,我们病例的结果证实,这种肿瘤病程高度侵袭性,预后不良。

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