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In situ detection of DNA damage in single cells or tissue sections by quantitative immunofluorescence microscopy.

作者信息

Baan R A, van den Berg P T, van Delft J H, Roza L, van der Meer E G, van der Wulp K J

机构信息

Department of Genetic Toxicology, TNO Medical Biological Laboratory, Rijswijk, The Netherlands.

出版信息

Prog Clin Biol Res. 1990;340A:101-12.

PMID:2201969
Abstract
摘要

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In situ detection of DNA damage in single cells or tissue sections by quantitative immunofluorescence microscopy.
Prog Clin Biol Res. 1990;340A:101-12.
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Use of the single-cell gel electrophoresis assay for the immunofluorescent detection of specific DNA damage.利用单细胞凝胶电泳分析法进行特定DNA损伤的免疫荧光检测。
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Synchronous fluorescence spectrophotometry of benzo[a]pyrene diol epoxide-DNA adducts: a tool for detection of in-vitro and in-vivo DNA damage by exposure to benzo[a]pyrene.苯并[a]芘二醇环氧化物-DNA加合物的同步荧光分光光度法:一种检测因接触苯并[a]芘而导致的体外和体内DNA损伤的工具。
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