Yasuda Masahiko, Inoue Takashi, Takakura Akira, Itoh Toshio
ICLAS Monitoring Center, Central Institute for Experimental Animals, Kawasaki, Kanagawa 210–0821, Japan.
J Vet Med Sci. 2012 Mar;74(3):357-9. doi: 10.1292/jvms.10-0187. Epub 2011 Oct 20.
A 3-year-old female common marmoset was euthanatized because of wasting. Grossly, a perforating lesion was present in the jejunum and hemorrhagic lesions in the cecum and colon. Histopathologically, these gross lesions were a perforated jejunal ulcer and necrotizing colitis, respectively. Necrotizing colitis was characterized by extensive mucosal necrosis along with numerous ribbon-shaped aseptate hyphae. These aseptate hyaline hyphae were positively stained with PAS and GMS, and reacted immunohistochemically with the antibody against the family Mucoraceae. This case was diagnosed as intestinal mucormycosis. This is the first report on mucormycosis in a common marmoset.
一只3岁雌性普通狨猴因消瘦而被安乐死。大体检查发现,空肠有一个穿孔性病变,盲肠和结肠有出血性病变。组织病理学检查显示,这些大体病变分别为空肠穿孔性溃疡和坏死性结肠炎。坏死性结肠炎的特征是广泛的黏膜坏死以及大量带状无隔菌丝。这些无隔透明菌丝经PAS和GMS染色呈阳性,并与抗毛霉科抗体发生免疫组化反应。该病例被诊断为肠道毛霉病。这是普通狨猴毛霉病的首例报告。