Chemistry Ben-Gurion University of the Negev Beer-Sheva, 84105, Israel.
Dalton Trans. 2012 Jan 7;41(1):32-43. doi: 10.1039/c1dt11404b. Epub 2011 Oct 24.
Olefin metathesis catalysed by ruthenium has emerged at the frontier of modern synthetic chemistry. The desire to enhance catalyst stability, gain control over the catalytic process and deepen the understanding of the mechanisms of metathesis has yielded a class of latent ruthenium precatalysts of delayed initiation and with switchable activity. One of the main methodologies developed for this purpose has been the introduction of tethered carbene ligands. Herein we track the evolution of ruthenium based metathesis catalysts bearing chelated alkylidenes, from the early oxygen Hoveyda type benzylidenes to the latent sulphur containing complexes.
钌催化的烯烃复分解反应已经出现在现代合成化学的前沿。为了提高催化剂的稳定性、控制催化过程并加深对复分解反应机制的理解，人们开发了一类具有延迟引发和可切换活性的潜在钌前催化剂。为此目的发展的主要方法之一是引入桥联卡宾配体。在此，我们追踪了带有螯合亚烷基的基于钌的复分解催化剂的演变，从早期的氧 Hoveyda 型苄基到含硫的潜伏复合物。
