Picard G, Leutenegger A F
Chirurgische Klinik des Rätischen Kantons- und Regionalspitals, Chur.
Ther Umsch. 1990 Jul;47(7):561-8.
As a rule, prophylactic antibiotics should only be given pre- or perioperatively as a single shot. Cephalosporins of the first and second generation are still quite effective and appear to be the most widely used drugs for this purpose. In some cases a second drug, like i.e. metronidazole, can be added. For each surgical specialty, the most appropriate prophylactic regimen is discussed.