[The use of immobilized and native proteolytic enzymes in treating inflammatory periodontal diseases].

.1% solution of native terrilytin, a proteolytic enzyme, and 5% profezyme, an immobilized enzyme, were used in the treatment of periodontal inflammations. To enhance the efficacy of enzyme therapy, the latter agent was combined with an antiseptic and pyrimidine-based methychlozyme paste including 5% of profezyme, 0.2% of chlorohexidine bigluconate, 0.2% of methyluracil, 30% of glycerin, and zinc oxide 74.6%. Use of immobilized and native proteolytic enzymes in therapy of patients with gingivitis and periodontitis permitted reducing the number of sessions 1.5-fold. Multiple-modality treatment was conducive to prolongation of the process remission up to 2 years in 52.31% of patients whereas in conventional therapy such remissions could be achieved in only 20%.