Orthopaedic Surgery Education Office, David Geffen School of Medicine at UCLA, Room 76-143 CHS 10833 Le Conte Avenue, Los Angeles, CA, 90095, USA,
Curr Rev Musculoskelet Med. 2011 Dec;4(4):221-30. doi: 10.1007/s12178-011-9095-6.
Rotator cuff repair is a common orthopedic procedure. Despite advances in surgical technique, the rotator cuff tendons often fail to heal after surgery. In recent years, a number of biologic strategies have been developed and tested to augment healing after rotator cuff repair. These strategies include allograft, extracellular matrices (ECMs), platelet rich plasma (PRP), growth factors, stem cells, and gene therapy. This chapter reviews the most current research on biologic augmentation of rotator cuff repair using these methods.
肩袖修复是一种常见的骨科手术。尽管手术技术不断进步,但肩袖肌腱在手术后往往无法愈合。近年来,已经开发和测试了许多生物策略来增强肩袖修复后的愈合。这些策略包括同种异体移植物、细胞外基质(ECMs)、富血小板血浆(PRP)、生长因子、干细胞和基因治疗。本章综述了使用这些方法增强肩袖修复的最新生物研究。