哌拉西林-他唑巴坦引起的低钾血症和代谢性碱中毒。
Piperacillin-tazobactam-induced hypokalemia and metabolic alkalosis.
机构信息
Department of Pediatrics, Lokmanya Tilak Municipal General Hospital and Medical College, Sion, Mumbai - 400 022, India.
出版信息
Indian J Pharmacol. 2011 Sep;43(5):609-10. doi: 10.4103/0253-7613.84986.
Abstract
Piperacillin/tazobactam is a commonly prescribed antibiotic and is generally considered safe. We report a case of a 2-year-old girl who developed hypokalemic metabolic alkalosis and bradycardia after receiving intravenous piperacillin-tazobactam for bronchopneumonia. Upon withdrawal of the drug, serum potassium normalized in 2 days. Hypokalemia is a serious adverse effect of piperacillin-tazobactam and should be suspected while treating patients with this drug. Early recognition and prompt withdrawal of the drug will result in lesser morbidity.
摘要
哌拉西林/他唑巴坦是一种常用的处方抗生素，通常被认为是安全的。我们报告了一例 2 岁女孩在因支气管肺炎接受静脉注射哌拉西林/他唑巴坦治疗后出现低钾代谢性碱中毒和心动过缓的病例。停用该药物后，血清钾在 2 天内恢复正常。低钾血症是哌拉西林/他唑巴坦的严重不良反应，在使用该药治疗患者时应怀疑其存在。早期识别和及时停药将降低发病率。
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本文引用的文献
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