Chitragar Sanjeev, Agarwal Shipra, Iyer Venkateswaran K, Mathur Sandeep R, Karak Asis K, Chharchhodawala Taher, Sharma Atul, Bakhshi Sameer
Department of Pathology, All India Institute of Medical Sciences, New Delhi- 110 029, India.
Cytojournal. 2011;8:17. doi: 10.4103/1742-6413.85496. Epub 2011 Sep 27.
Extramedullary deposits may be the presenting feature of acute myeloid leukemia. An early and accurate diagnosis on cytology will aid in correct patient management. This is especially true for patients with acute megakaryoblastic leukemia (AML M7), where bone marrow aspiration may yield only a dry tap. While cytomorphological features of myeloid sarcoma of other types are well recognized due to its rarity, there are only two case reports discussing the morphological details of megakaryoblastic differentiation on aspiration cytology. We present the case of a 25-year-old patient with extramedullary involvement of lymph node and cerebrospinal fluid by AML M7, describing in detail, the morphological features on aspiration as well as exfoliative cytology.
髓外沉积物可能是急性髓系白血病的首发特征。对细胞学进行早期准确诊断将有助于正确的患者管理。对于急性巨核细胞白血病（AML M7）患者尤其如此，此类患者骨髓穿刺可能仅抽出干抽物。虽然其他类型的髓系肉瘤的细胞形态学特征因其罕见而广为人知，但仅有两篇病例报告讨论了穿刺细胞学检查中巨核细胞分化的形态学细节。我们报告了一例25岁AML M7患者出现淋巴结和脑脊液髓外受累的病例，详细描述了穿刺及脱落细胞学检查的形态学特征。
