Instituto de Neurociencias y Centro de Investigaciones Biomédicas, Universidad de Granada, Granada, Spain.
J Sex Med. 2012 Feb;9(2):542-9. doi: 10.1111/j.1743-6109.2011.02513.x. Epub 2011 Oct 24.
Sexual dysfunction has been associated with several chronic pain conditions, including fibromyalgia. However, the literature on sexual functioning in patients with fibromyalgia is limited and restricted to female patients.
The aim of our study was to evaluate sexual functioning in female and male patients with fibromyalgia compared with healthy controls.
Sexual functioning was evaluated using the Spanish validated version of the Changes in Sexual Functioning Questionnaire (CSFQ).
We used baseline data from several studies performed in adult patients with fibromyalgia (American College of Rheumatology criteria) of both sexes in which sexual functioning was included in the clinical evaluation. As a control group, we selected an age-matched group of healthy subjects. We calculated the proportion of patients exhibiting sexual dysfunction (i.e., a CSFQ total score equal to or lower than 41 in females and 47 in males). CSFQ scores for patients and controls were compared, and the effect sizes for the difference of means were calculated.
Our sample comprised 293 patients with fibromyalgia (276 females and 17 males) and 86 healthy controls (72 females and 14 males). The frequency of sexual dysfunction was significantly higher in patients with fibromyalgia than in controls for both females (86.9% vs. 23.6%; relative risk [RR] 3.7, 95% confidence interval [CI], 2.4-5.6) and males (76.5% vs. 6.7%; RR 11.5, 95% CI, 1.7-77.6). We found significantly worse sexual functioning for all dimensions in both female and male patients with fibromyalgia. Effect sizes for the difference in mean scores of the CSFQ were large overall and for all dimensions in both females and males.
Our results show that sexual dysfunction is common in patients with fibromyalgia. The disease seems to deeply affect all dimensions of sexual functioning in both females and males.
性功能障碍与多种慢性疼痛疾病有关,包括纤维肌痛。然而,纤维肌痛患者性功能的相关文献有限,且仅限于女性患者。
本研究旨在评估纤维肌痛女性和男性患者与健康对照组相比的性功能。
性功能采用西班牙验证的性功能变化问卷(CSFQ)进行评估。
我们使用了几项在两性纤维肌痛患者(美国风湿病学会标准)中进行的研究的基线数据,这些研究将性功能纳入临床评估。作为对照组,我们选择了一组年龄匹配的健康受试者。我们计算了表现出性功能障碍的患者比例(即女性 CSFQ 总分等于或低于 41 分,男性 47 分)。比较了患者和对照组的 CSFQ 评分,并计算了均值差异的效应大小。
我们的样本包括 293 名纤维肌痛患者(276 名女性和 17 名男性)和 86 名健康对照组(72 名女性和 14 名男性)。女性纤维肌痛患者性功能障碍的发生率显著高于对照组(86.9%比 23.6%;相对风险[RR]3.7,95%置信区间[CI]2.4-5.6)和男性(76.5%比 6.7%;RR 11.5,95%CI 1.7-77.6)。我们发现所有纤维肌痛女性和男性患者的所有维度的性功能均明显下降。CSFQ 平均评分差异的总体效应大小较大,且在女性和男性中所有维度均较大。
我们的结果表明,性功能障碍在纤维肌痛患者中很常见。该疾病似乎严重影响了女性和男性患者所有维度的性功能。