Division of Endocrinology, Miller School of Medicine, University of Miami, 1400 NW 10th Avenue, Dominion Towers, Suite 809, Miami, FL 33136, USA.
Rheum Dis Clin North Am. 2011 Aug;37(3):453-70, vii. doi: 10.1016/j.rdc.2011.07.001.
Osteoporosis-related fractures are associated with significant morbidity, mortality, and health care expenditure worldwide. The low sensitivity of bone density testing alone to predict fractures has led to the development of a variety of fracture assessment tools that use the combination of bone density and clinical risk factors to improve the prediction of low-trauma fractures. These fracture assessment tools quantitatively predict the 10-year probability of hip and major osteoporosis-related fractures, and can be used with various intervention strategies to effectively intervene with cost-effective therapies to prevent future fractures.
骨质疏松相关骨折与全球范围内的重大发病率、死亡率和医疗支出有关。单纯骨密度检测对骨折的敏感性较低，因此开发了多种骨折评估工具，这些工具结合了骨密度和临床危险因素，以提高对低创伤性骨折的预测能力。这些骨折评估工具定量预测了 10 年内髋部和主要骨质疏松性骨折的概率，并可与各种干预策略一起使用，以通过具有成本效益的治疗方法进行有效干预，预防未来的骨折。
