Graduate School of Life and Environmental Sciences, University of Tsukuba 1-1-1, Tennodai, Tsukuba 305-8572, Japan.
Bioresour Technol. 2012 Apr;109:287-91. doi: 10.1016/j.biortech.2011.09.127. Epub 2011 Oct 7.
Optimum conditions of temperature, salinity and glucose concentration were investigated for squalene production of the strain of Aurantiochytrium sp. 18 W-13a, with a high content of squalene. Squalene production by this strain was optimum at 25 °C, 25-50% seawater concentration and 2-6% glucose concentration. When this strain was grown in the optimum condition, the squalene content and production of approximately 171 mg/g dry weight and 0.9 g/L were much higher than that previously reported in thraustochytrids, plants and yeasts, respectively. Therefore, 18 W-13a could be used as an alternative source of commercial squalene.
研究了富含角鲨烯的 Aurantiochytrium sp. 18W-13a 菌株的角鲨烯生产的最适温度、盐度和葡萄糖浓度条件。该菌株的角鲨烯生产最适温度为 25°C，海水浓度为 25-50%，葡萄糖浓度为 2-6%。当该菌株在最适条件下生长时，角鲨烯含量和产量分别约为 171mg/g 干重和 0.9g/L，明显高于先前在厚壳贻贝类、植物和酵母中报道的值。因此，18W-13a 可以作为商业角鲨烯的替代来源。
