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急性肠系膜上动脉血栓栓塞性闭塞的诊断与处理

Diagnosis and management of acute thromboembolic occlusion of the superior mesenteric artery.

作者信息

Liu Peng, Ren Shiyan, Lin Fan, Yang Yuguan, Ye Zhidong

机构信息

Department of Surgerey, China-Japan Friendship Hospital, Beijing, China.

出版信息

Hepatogastroenterology. 2011 Nov-Dec;58(112):1893-7. doi: 10.5754/hge11251.

Abstract

BACKGROUND/AIMS: Acute occlusion of the superior mesenteric artery (SMA) is rare and difficult to diagnose, the associated morbidity and mortality are still high. Here we review our experience in diagnosis and treatment of acute embolic occlusion of the SMA, determine factors for surgical complications and patient survival.

METHODOLOGY

Thirty-seven patients with acute embolic occlusion of the SMA between 1993 and 2009 were retrospectively analyzed.

RESULTS

There were 23 (62.16%) men and 14 (37.84%) women, with a mean age of 59 years. Abdominal pain associated with nausea and vomiting was present in 32 (86.49%) patients. Twenty patients had atrial fibrillation. Emergency mesenteric arteriography was performed in 89.19% (33/37) patients. Fifteen patients were managed medically and 17 patients underwent surgical exploration. Of the 37 patients treated, 21 (56.75%) survived and were grouped as the survival group, 16 (43.24%) died and were grouped as the mortality group. In comparison with the survival group, patients in the mortality group had been delayed longer before definitive treatment and had higher white blood cell counts and proportion of neutral cells, shorter length of remaining bowel after surgery and higher incidence of renal insufficiency.

CONCLUSIONS

Early diagnosis and intervention would improve the outcomes of patients with SMA. Identification of viable intestine and resection of the necrotic bowel during surgery are critical in improving the survival rate.

摘要

背景/目的:肠系膜上动脉(SMA)急性闭塞较为罕见且诊断困难,其相关的发病率和死亡率仍然很高。在此,我们回顾我们在SMA急性栓塞性闭塞诊断和治疗方面的经验,确定手术并发症和患者生存的相关因素。

方法

回顾性分析1993年至2009年间37例SMA急性栓塞性闭塞患者的资料。

结果

男性23例(62.16%),女性14例(37.84%),平均年龄59岁。32例(86.49%)患者出现腹痛并伴有恶心呕吐。20例患者有房颤。89.19%(33/37)的患者接受了急诊肠系膜动脉造影。15例患者接受内科治疗,17例患者接受手术探查。在接受治疗的37例患者中,21例(56.75%)存活并被归为生存组,16例(43.24%)死亡并被归为死亡组。与生存组相比,死亡组患者在明确治疗前的延误时间更长,白细胞计数和中性粒细胞比例更高,术后剩余肠管长度更短,肾功能不全的发生率更高。

结论

早期诊断和干预可改善SMA患者的预后。术中识别存活肠管并切除坏死肠管对提高生存率至关重要。

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