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肢端皮肤血管骨瘤

Acral angioosteoma cutis.

作者信息

Lee Eun-Ju, Lee Jong-Ho, Shin Min-Kyung, Lee Sung-Won, Haw Choong-Rim

机构信息

Department of Dermatology, School of Medicine, Kyung Hee University, Seoul, Korea.

出版信息

Ann Dermatol. 2011 Sep;23 Suppl 1(Suppl 1):S105-7. doi: 10.5021/ad.2011.23.S1.S105. Epub 2011 Sep 30.

Abstract

Acral angioosteoma cutis is a rare disease first described in 2006 that is characterized by vascular proliferation with ossification at the acral area, and which bears clinical similarity to pyogenic granuloma. However, there is no lobular pattern in the capillary proliferation that is a typical histopathological feature in pyogenic granuloma. Metaplastic cutaneous ossification is associated with multiple skin diseases and inflammatory conditions such as scars, nevi, basal cell carcinomas, pilomatricomas, chondroid syringomas, and venous stasis. It is rarely associated with vascular proliferation diseases like hemangiomas and pyogenic granulomas. We report a case of capillary proliferation with ectopic bone formation in a 43-year-old female who presented with an ulcerative, dome-shaped subungual nodule on the left fourth toe, which appeared to be a pyogenic granuloma. Because the biopsy findings showed no lobular capillary proliferation, we determined that this case was consistent with acral angioosteoma cutis.

摘要

肢端皮肤血管骨瘤是一种于2006年首次被描述的罕见疾病,其特征为肢端区域血管增生伴骨化,临床与化脓性肉芽肿相似。然而,其毛细血管增生无小叶状模式,而这是化脓性肉芽肿典型的组织病理学特征。化生皮肤骨化与多种皮肤疾病及炎症状况相关,如瘢痕、痣、基底细胞癌、毛母质瘤、软骨样汗腺瘤及静脉淤积。它很少与血管瘤和化脓性肉芽肿等血管增生性疾病相关。我们报告一例43岁女性病例,其左足第四趾出现溃疡性、圆顶状甲下结节,看似化脓性肉芽肿,活检显示有毛细血管增生伴异位骨形成。由于活检结果未显示小叶状毛细血管增生,我们判定该病例符合肢端皮肤血管骨瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd5c/3199402/88068471017f/ad-23-S105-g001.jpg

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