生长激素治疗史。
History of growth hormone therapy.
作者信息
Ayyar Vageesh S
机构信息
Department of Endocrinology, St. John's Medical College, Bangalore, India.
出版信息
Indian J Endocrinol Metab. 2011 Sep;15 Suppl 3(Suppl3):S162-5. doi: 10.4103/2230-8210.84852.
Abstract
Although the importance of the pituitary gland for growth was recognized in late 19(th) century, Growth hormone (GH) therapy was made available for severely GH-deficient children and adolescents only in late 1950s. Use of GH for other conditions was limited because of the limited supply of human pituitary-derived hormone. With unlimited availability of recombinant human GH (rhGH), the scenario of GH treatment has been changed enormously. Currently there is ever increasing list of indications of GH treatment in children, adolescents, and adults.
摘要
尽管垂体对生长的重要性在19世纪后期就已被认识到，但生长激素（GH）疗法直到20世纪50年代后期才用于严重生长激素缺乏的儿童和青少年。由于人垂体来源激素供应有限，生长激素在其他病症中的应用受到限制。随着重组人生长激素（rhGH）的无限供应，生长激素治疗的情况发生了巨大变化。目前，生长激素在儿童、青少年和成人中的治疗适应证越来越多。
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