Szilágyi A, Feledi E, Csaba I, Pejtsik B
Pécsi Orvostudományi Egyetem Szülészeti és Nögyógyászati Klinika.
Orv Hetil. 1990 Jul 22;131(29):1585-8.
Oral glucose tolerance testing (oGTT) was performed according to WHO criteria among obese pregnant women (body mass index greater than 28) who were recruited with the help of computerized pregnancy counselling data base. oGTT was carried out for the first time between gestational ages of 16-20 weeks, and it was repeated monthly as far as possible. Gestational diabetes was diagnosed in 4 cases out of 50 obese patients. Two gestational diabetic patients needed insulin treatment. According to computerized data obese patients have significantly higher risk of having macrosomic infants and/or intrauterine death. Fasting blood glucose values of obese pregnant women were significantly higher in all the gestational ages. It is emphasized that obesity means a risk factor for gestational diabetes, but the onset of carbohydrate intolerance may be prevented or diagnosed as early as possible with the help of repeated oGTT during pregnancy and dietary counselling. In this way fetal complications, especially macrosomia will not develop.
在借助计算机化妊娠咨询数据库招募的肥胖孕妇(体重指数大于28)中,根据世界卫生组织标准进行口服葡萄糖耐量试验(oGTT)。oGTT在孕龄16至20周之间首次进行,并尽可能每月重复一次。50例肥胖患者中有4例被诊断为妊娠期糖尿病。两名妊娠期糖尿病患者需要胰岛素治疗。根据计算机化数据,肥胖患者生出巨大儿和/或宫内死亡的风险显著更高。肥胖孕妇在所有孕周的空腹血糖值均显著更高。需要强调的是,肥胖是妊娠期糖尿病的一个风险因素,但通过孕期重复进行oGTT和饮食咨询,碳水化合物不耐受的发生可以尽早预防或诊断。这样胎儿并发症,尤其是巨大儿就不会出现。