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Human and mouse lactate dehydrogenase genes A (muscle), B (heart), and C (testis): protein structure, genomic organization, regulation of expression, and molecular evolution.

作者信息

Li S S

机构信息

Laboratory of Genetics, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina 27709.

出版信息

Prog Clin Biol Res. 1990;344:75-99.

PMID:2203060
Abstract
摘要

相似文献

1
Human and mouse lactate dehydrogenase genes A (muscle), B (heart), and C (testis): protein structure, genomic organization, regulation of expression, and molecular evolution.人类和小鼠的乳酸脱氢酶基因A(肌肉型)、B(心脏型)和C(睾丸型):蛋白质结构、基因组组织、表达调控及分子进化
Prog Clin Biol Res. 1990;344:75-99.
2
Expression of the human lactate dehydrogenase-C gene in transgenic mice.人乳酸脱氢酶-C基因在转基因小鼠中的表达。
Prog Clin Biol Res. 1990;344:441-52.
3
The cDNA and protein sequences of mouse lactate dehydrogenase B. Molecular evolution of vertebrate lactate dehydrogenase genes A (muscle), B (heart) and C (testis).小鼠乳酸脱氢酶B的cDNA和蛋白质序列。脊椎动物乳酸脱氢酶基因A(肌肉)、B(心脏)和C(睾丸)的分子进化。
Eur J Biochem. 1990 Apr 30;189(2):215-20. doi: 10.1111/j.1432-1033.1990.tb15479.x.
4
Human testicular lactate dehydrogenase-C gene is interrupted by six introns at positions homologous to those of LDH-A (muscle) and LDH-B (heart) genes.人类睾丸乳酸脱氢酶-C基因在与乳酸脱氢酶-A(肌肉)和乳酸脱氢酶-B(心脏)基因同源的位置被六个内含子中断。
Biochem Biophys Res Commun. 1989 Mar 15;159(2):579-83. doi: 10.1016/0006-291x(89)90033-8.
5
Lactate dehydrogenase isoenzymes A (muscle), B (heart) and C (testis) of mammals and the genes coding for these enzymes.哺乳动物的乳酸脱氢酶同工酶A(肌肉型)、B(心脏型)和C(睾丸型)以及编码这些酶的基因。
Biochem Soc Trans. 1989 Apr;17(2):304-7. doi: 10.1042/bst0170304.
6
Molecular structure, developmental regulation, and evolution of the gene encoding glycerol-3-phosphate dehydrogenase isozymes in Drosophila melanogaster.黑腹果蝇中编码3-磷酸甘油脱氢酶同工酶的基因的分子结构、发育调控及进化
Prog Clin Biol Res. 1990;344:341-74.
7
Cloning and characterization of a novel intronless lactate dehydrogenase gene in human testis.人睾丸中一个新型无内含子乳酸脱氢酶基因的克隆与鉴定
Int J Mol Med. 2005 Jun;15(6):949-53.
8
Marsupial and monotreme lactate dehydrogenase isozymes: phylogeny, ontogeny, and homology with eutherian mammals.
J Exp Zool. 1973 Apr;184(1):127-48. doi: 10.1002/jez.1401840109.
9
Human testis-specific lactate dehydrogenase-C promoter drives overexpression of mouse lactate dehydrogenase-1 cDNA in testes of transgenic mice.人类睾丸特异性乳酸脱氢酶-C启动子驱动小鼠乳酸脱氢酶-1 cDNA在转基因小鼠睾丸中过表达。
J Exp Zool. 1998;282(1-2):171-8.
10
Characterization of isoforms and genomic organization of mouse calumenin.小鼠钙网蛋白同工型的表征及基因组结构
Gene. 2004 Mar 3;327(2):185-94. doi: 10.1016/j.gene.2003.10.014.

引用本文的文献

1
Lactate Dehydrogenase A or B Knockdown Reduces Lactate Production and Inhibits Breast Cancer Cell Motility .乳酸脱氢酶A或B基因敲低可减少乳酸生成并抑制乳腺癌细胞迁移。
Front Pharmacol. 2021 Oct 20;12:747001. doi: 10.3389/fphar.2021.747001. eCollection 2021.
2
Molecular cloning and characterization of lactate dehydrogenase gene 1 in the silkworm, Bombyx mori.家蚕乳酸脱氢酶基因 1 的分子克隆与特性分析。
Mol Biol Rep. 2011 Mar;38(3):1853-60. doi: 10.1007/s11033-010-0302-0. Epub 2010 Sep 18.
3
Ultracentrifugation studies of the location of the site involved in the interaction of pig heart lactate dehydrogenase with acidic phospholipids at low pH. A comparison with the muscle form of the enzyme.
在低 pH 值下研究与酸性磷脂相互作用的部位在猪心乳酸脱氢酶中的位置的超速离心研究。与肌肉形式的酶进行比较。
Cell Mol Biol Lett. 2007 Sep;12(3):378-95. doi: 10.2478/s11658-007-0010-5. Epub 2007 Mar 3.
4
M-LDH serves as a sarcolemmal K(ATP) channel subunit essential for cell protection against ischemia.M型乳酸脱氢酶作为肌膜ATP敏感性钾通道亚基,对细胞抵抗缺血至关重要。
EMBO J. 2002 Aug 1;21(15):3936-48. doi: 10.1093/emboj/cdf388.