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Targeting JunD: a potential strategy to counteract hormone-refractory prostate cancer.

作者信息

Sarkar Devanand, Wang Xiang-Yang, Fisher Paul B

出版信息

Cell Cycle. 2011 Oct 15;10(20):3433. doi: 10.4161/cc.10.20.17668.

DOI:10.4161/cc.10.20.17668
PMID:22030692
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3356832/
Abstract
摘要

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Targeting JunD: a potential strategy to counteract hormone-refractory prostate cancer.靶向JunD:一种对抗激素难治性前列腺癌的潜在策略。
Cell Cycle. 2011 Oct 15;10(20):3433. doi: 10.4161/cc.10.20.17668.
2
Prostate cancer: JunD, Gadd45a and Gadd45g as therapeutic targets.前列腺癌:JunD、生长停滞和DNA损伤诱导蛋白45α(Gadd45a)及生长停滞和DNA损伤诱导蛋白45γ(Gadd45g)作为治疗靶点
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3
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本文引用的文献

1
JunD-mediated repression of GADD45α and γ regulates escape from cell death in prostate cancer.JunD 介导的 GADD45α 和 γ 的抑制调节前列腺癌细胞逃避死亡。
Cell Cycle. 2011 Aug 1;10(15):2583-91. doi: 10.4161/cc.10.15.16057.
2
Androgen receptor requires JunD as a coactivator to switch on an oxidative stress generation pathway in prostate cancer cells.雄激素受体需要 JunD 作为共激活因子来开启前列腺癌细胞中的氧化应激生成途径。
Cancer Res. 2010 Jun 1;70(11):4560-8. doi: 10.1158/0008-5472.CAN-09-3596. Epub 2010 May 11.
3
Growth arrest and DNA damage-45 alpha (GADD45alpha).生长停滞与DNA损伤诱导蛋白45α(GADD45α)
Int J Biochem Cell Biol. 2009 May;41(5):986-9. doi: 10.1016/j.biocel.2008.06.018. Epub 2008 Aug 5.
4
Multiple facets of junD gene expression are atypical among AP-1 family members.JunD基因表达的多个方面在AP-1家族成员中是非典型的。
Oncogene. 2008 Aug 14;27(35):4757-67. doi: 10.1038/onc.2008.120. Epub 2008 Apr 21.
5
Blockage of NF-kappaB induces serine 15 phosphorylation of mutant p53 by JNK kinase in prostate cancer cells.在前列腺癌细胞中,NF-κB的阻断通过JNK激酶诱导突变型p53的丝氨酸15磷酸化。
Cell Cycle. 2005 Sep;4(9):1247-53. doi: 10.4161/cc.4.9.1966. Epub 2005 Sep 24.
6
Constitutive activation of nuclear factor kappaB p50/p65 and Fra-1 and JunD is essential for deregulated interleukin 6 expression in prostate cancer.核因子κB p50/p65、Fra-1和JunD的组成性激活对于前列腺癌中白细胞介素6表达失调至关重要。
Cancer Res. 2003 May 1;63(9):2206-15.
7
A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK.一个应激诱导的GADD45样蛋白家族介导应激反应性MTK1/MEKK4丝裂原活化蛋白激酶激酶激酶的激活。
Cell. 1998 Nov 13;95(4):521-30. doi: 10.1016/s0092-8674(00)81619-0.
8
Mammalian GADD34, an apoptosis- and DNA damage-inducible gene.哺乳动物的生长停滞和DNA损伤诱导基因34(GADD34),一种可被凋亡和DNA损伤诱导的基因。
J Biol Chem. 1997 May 23;272(21):13731-7. doi: 10.1074/jbc.272.21.13731.
9
Mammalian genes coordinately regulated by growth arrest signals and DNA-damaging agents.受生长停滞信号和DNA损伤剂协同调控的哺乳动物基因。
Mol Cell Biol. 1989 Oct;9(10):4196-203. doi: 10.1128/mcb.9.10.4196-4203.1989.