Hanada R, Yaginuma A, Hayashi Y, Inaba T, Yamamoto K, Imaizumi S, Hirata A, Sugawara T, Aihara T, Miyakawa T
Dept. of Hematology/Oncology, Saitama Children's Medical Center.
Gan To Kagaku Ryoho. 1990 Sep;17(9):1937-9.
Stage I neuroblastoma in a seven-year-girl have had local recurrence with bone metastasis. Second surgery was performed after the aggressive chemotherapy including cisplatin, VP16, cyclophosphamide, vincristine and doxorubicin. She underwent allogeneic bone marrow transplantation from her HLA identical brother, following the preparative regimen consisting of high-dose melphalan and total body irradiation (12 Gy). Clinical course after the transplantation was uneventful. She is still alive with no evidence of disease for twenty-eight months after the transplantation. It is suggested that bone marrow transplantation is an effective way of therapy even in a patient with relapsed neuroblastoma.
