Service de Radiologie, Hôpital Maison Blanche, Reims, France.
AJNR Am J Neuroradiol. 2012 Mar;33(3):469-73. doi: 10.3174/ajnr.A2771. Epub 2011 Oct 27.
Matrix coils have been developed to prevent aneurysm recanalization. Midterm anatomic results in a prospective multicenter consecutive series including patients treated with GDC or Matrix coils for ruptured aneurysms are presented.
Five hundred seventeen patients harboring ruptured aneurysms were treated with GDC (276 patients) or Matrix coils (241 patients). Postoperative and midterm anatomic results were evaluated anonymously and independently using the Modified Montreal Scale (complete occlusion, neck remnant, and aneurysm remnant).
In the midterm follow-up (mean, 16.7 months in the GDC group and 15.4 months in the Matrix group), complete occlusion was reported in 95/276 aneurysms (34.4%) in the GDC group and 80/241 (33.2%) in the Matrix group, neck remnant in 127/276 (46.0%) in the GDC group and 118/241 (49.0%) in the Matrix group, and aneurysm remnant in 54/276 (19.6%) in the GDC group and 43/241 (17.8%) in the Matrix group. Evolution of aneurysm occlusion was improvement in 35/272 aneurysms (12.9%) in the GDC group and 27/239 (11.3%) in the Matrix group, stable situation in 98/272 (36.0%) in the GDC group and 97/239 (40.6%) in the Matrix group, and worsening in 139/272 (51.1%) in the GDC group and 115/239 (48.1%) in the Matrix group. A total of 32/517 patients were retreated during the follow-up period: 9/276 (3.3%) in the GDC group and 23/241 (9.5%) in the Matrix group (P = .003).
In this study, midterm anatomic results and evolution of aneurysm occlusion were not different in patients with ruptured aneurysms treated with GDC or Matrix coils.
矩阵线圈的开发是为了防止动脉瘤再通。本研究报告了前瞻性多中心连续系列中使用 GDC 或 Matrix 线圈治疗破裂动脉瘤的中期解剖结果。
517 例破裂性动脉瘤患者接受 GDC(276 例)或 Matrix 线圈(241 例)治疗。术后和中期解剖结果采用改良蒙特利尔量表(完全闭塞、颈部残留和动脉瘤残留)进行匿名和独立评估。
在中期随访(GDC 组平均 16.7 个月,Matrix 组平均 15.4 个月)中,GDC 组 276 例动脉瘤中有 95 例(34.4%)达到完全闭塞,Matrix 组 241 例中有 80 例(33.2%)达到完全闭塞,GDC 组 276 例中有 127 例(46.0%)存在颈部残留,Matrix 组 241 例中有 118 例(49.0%)存在颈部残留,GDC 组 276 例中有 54 例(19.6%)存在动脉瘤残留,Matrix 组 241 例中有 43 例(17.8%)存在动脉瘤残留。GDC 组 272 例动脉瘤中有 35 例(12.9%)得到改善,Matrix 组 239 例中有 27 例(11.3%)得到改善,GDC 组 272 例中有 98 例(36.0%)稳定,Matrix 组 239 例中有 97 例(40.6%)稳定,GDC 组 272 例中有 139 例(51.1%)恶化,Matrix 组 239 例中有 115 例(48.1%)恶化。在随访期间,共有 32 例/517 例患者需要再次治疗:GDC 组 9 例(3.3%),Matrix 组 23 例(9.5%)(P =.003)。
在这项研究中,接受 GDC 或 Matrix 线圈治疗的破裂性动脉瘤患者的中期解剖结果和动脉瘤闭塞的演变没有差异。