Nonchev S, Tsanev R
Institute of Molecular Biology, Bulgarian Academy of Sciences, Sofia.
Mol Reprod Dev. 1990 Jan;25(1):72-6. doi: 10.1002/mrd.1080250113.
The protamine to histone replacement in fertilized mouse eggs was studied by using antibodies to these proteins. Its course was followed with respect to DNA replication by autoradiography of 3H-thymidine-labeled fertilized eggs. It was found that protamines were replaced by histones before the onset of DNA replication.