Division of Rhinology and Sinus Surgery, Oregon Sinus Center, Department of Otolaryngology-Head and Neck Surgery, Oregon Health and Science University, Portland, Oregon 97239, USA.
Laryngoscope. 2011 Dec;121(12):2679-83. doi: 10.1002/lary.22361. Epub 2011 Oct 27.
OBJECTIVES/HYPOTHESIS: To determine if chronic rhinosinusitis (CRS)-specific health-related quality-of-life (HRQoL) outcomes are affected by concurrent septoplasty performed during endoscopic sinus surgery (ESS) for medically refractory CRS.
Prospective, multicenter cohort study.
A total of 221 patients with medically refractory CRS without nasal polyposis who elected primary ESS were included in this study. Patients were dichotomized into two cohorts: concurrent septoplasty (n = 108) or no septoplasty (n = 113) during ESS. The main outcomes of interest included two CRS-specific HRQoL instruments: the Rhinosinusitis Disability Index (RSDI) and the Chronic Sinusitis Survey (CSS). Symptom presentation was assessed using eight sinonasal visual analog scale (VAS) symptom scores.
There were no differences in CRS-specific HRQoL improvements on all RSDI and CSS measures following ESS between cohorts with or without septoplasty (all P > .05). In patients with medically refractory CRS, the presence of septal deviation did not result in a different CRS-specific symptom presentation compared to patients without septal deviation (all baseline VAS symptom score comparisons P > .295).
To optimize nasal patency and improve surgical access, septoplasty is commonly performed during ESS. Based on the results of this study, concurrent septoplasty does not appear to affect CRS-specific HRQoL or symptom outcomes and does not function as a confounding factor in HRQoL improvement.
目的/假设:确定内镜鼻窦手术(ESS)治疗药物难治性慢性鼻-鼻窦炎(CRS)时同期行鼻中隔成形术是否会影响 CRS 特异性健康相关生活质量(HRQoL)结局。
前瞻性、多中心队列研究。
本研究纳入了 221 例无鼻息肉的药物难治性 CRS 患者,这些患者选择行初次 ESS。患者分为两组:ESS 同期行鼻中隔成形术(n = 108)或不行鼻中隔成形术(n = 113)。主要观察结局包括两个 CRS 特异性 HRQoL 量表:鼻-鼻窦炎患者生活质量调查问卷(RSDI)和慢性鼻窦炎调查量表(CSS)。使用 8 个鼻-鼻窦视觉模拟量表(VAS)症状评分评估症状表现。
ESS 后,鼻中隔成形术组和对照组在所有 RSDI 和 CSS 测量指标上的 CRS 特异性 HRQoL 改善情况均无差异(所有 P >.05)。在药物难治性 CRS 患者中,鼻中隔偏曲的存在与无鼻中隔偏曲的患者相比,并未导致不同的 CRS 特异性症状表现(所有基线 VAS 症状评分比较 P >.295)。
为了优化鼻腔通畅度并改善手术入路,鼻中隔成形术通常在 ESS 期间进行。基于本研究的结果,同期行鼻中隔成形术似乎不会影响 CRS 特异性 HRQoL 或症状结局,并且不会成为 HRQoL 改善的混杂因素。