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尼日利亚伊巴丹市城区人口的新生儿死亡率。

Neonatal mortality in an urban population in Ibadan, Nigeria.

机构信息

Department of Paediatrics, University College Hospital, Ibadan, Nigeria.

出版信息

Pediatr Neonatol. 2011 Oct;52(5):243-50. doi: 10.1016/j.pedneo.2011.06.001. Epub 2011 Aug 4.

Abstract

BACKGROUND

Neonatal mortality remains a major contributor to death among children younger than 5 years in developing countries. This study was undertaken to determine the neonatal mortality rate (NMR), causes of death, and associated risk factors among hospital live births in a suburban population in Nigeria.

PATIENTS AND METHODS

A total of 1058 consecutive live newborns at Adeoyo Maternity Hospital, Ibadan, were enrolled at birth and followed up in their homes for 28 days. The causes of death were extracted from hospital records, and verbal autopsy was used to determine the causes of death outside the hospital.

RESULTS

The NMR was 32.1 per 1000 live births. The leading causes of death were severe perinatal asphyxia (79.4%), low birth weight (LBW: 55.9%), and infections (41.2%). The associated risk factors were lack of antenatal care [relative risk (RR)=45.18; 95% confidence interval (CI)=7.80, 261.60]; prolonged rupture of membranes (RR=4.47; 95% CI=1.95, 10.25); maternal peripartal fever (RR=5.42; 95% CI=2.35, 12.52); prematurity (RR=7.53; 95% CI=4.91, 11.55); and LBW (RR=5.50; 95% CI=3.88, 7.80).

CONCLUSION

NMR is high among hospital live births in Ibadan. There is a need for programs encouraging the use of antenatal care, improving skills on neonatal resuscitation and care of LBW infants; as well as implementation of community-based newborn survival strategies.

摘要

背景

在发展中国家,新生儿死亡仍然是 5 岁以下儿童死亡的主要原因。本研究旨在确定尼日利亚郊区人群中医院活产儿的新生儿死亡率(NMR)、死亡原因和相关危险因素。

患者和方法

在伊巴丹的阿德约伊妇产科医院,共有 1058 例连续的活产新生儿在出生时入组,并在其家中随访 28 天。死亡原因从医院记录中提取,采用口头尸检确定医院外的死亡原因。

结果

NMR 为每 1000 例活产儿 32.1 例。主要死亡原因是严重围产期窒息(79.4%)、低出生体重(LBW:55.9%)和感染(41.2%)。相关危险因素包括缺乏产前保健[相对风险(RR)=45.18;95%置信区间(CI)=7.80,261.60];胎膜延长破裂(RR=4.47;95% CI=1.95,10.25);产妇围产期发热(RR=5.42;95% CI=2.35,12.52);早产(RR=7.53;95% CI=4.91,11.55)和 LBW(RR=5.50;95% CI=3.88,7.80)。

结论

伊巴丹医院活产儿的 NMR 较高。需要制定方案鼓励使用产前保健,提高新生儿复苏和 LBW 婴儿护理技能;并实施基于社区的新生儿生存策略。

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