发育中的人类大脑：新兴儿科神经学家需要了解的知识。

The developing human brain: what the emerging pediatric neurologist needs to know.

机构信息

Department of Pathology (Neuropathology), Children's Hospital, Los Angeles, CA 90027, USA.

出版信息

Semin Pediatr Neurol. 2011 Jun;18(2):124-7. doi: 10.1016/j.spen.2011.05.014.

DOI:10.1016/j.spen.2011.05.014

PMID:22036498

Abstract

The developing human brain is a remarkable tissue. Embryonic and fetal brain growth is largely genetically controlled. Environmental factors become increasingly important with advancing development. The young pediatric neurologist who masters a little fundamental neuroanatomy, developmental neuroanatomy, and developmental neuropathology will be able to interpret neuroimages and abnormal development because he or she understands the structural changes in growth failures, hemorrhages, acquired lesions, white matter abnormalities, vascular disease and malformations, ventriculomegaly, tumors, infectious disease, common malformations, degenerative and demyelinative diseases, toxic, and metabolic diseases.

摘要

发育中的人脑是一种非凡的组织。胚胎和胎儿大脑的生长在很大程度上受遗传控制。随着发育的推进，环境因素变得越来越重要。掌握了一些基本神经解剖学、发育神经解剖学和发育神经病理学知识的年轻儿科神经科医生，能够解读神经影像和异常发育，因为他或她了解生长失败、出血、获得性病变、白质异常、血管疾病和畸形、脑室扩大、肿瘤、传染病、常见畸形、退行性和脱髓鞘疾病、中毒和代谢疾病等结构变化。