科学故事：苍蝇、飞机、蠕虫和激光。
Science stories: flies, planes, worms, and lasers.
机构信息
Biochemistry and Molecular Biology, Pennsylvania State University, University Park, PA 16802, USA.
出版信息
Mol Biol Cell. 2011 Nov;22(21):3921-2. doi: 10.1091/mbc.E11-05-0450.
Abstract
"Tell a story," my mother instructs her graduate students as they prepare their talks. I will make use of her advice here, and will tell several short stories. The themes revolve around the practice of science-what motivates us to go into science and how we choose questions once we get there. I also touch on progress in scientific tools, teaching, good mentors, and good colleagues, all of which contribute to making a career in science constantly compelling.
摘要
“讲故事，”我的母亲指导她的研究生，因为他们准备他们的谈话。我将在这里利用她的建议，并将讲述几个小故事。主题围绕着科学实践——激励我们进入科学的动力是什么，以及一旦进入科学，我们如何选择问题。我还谈到了科学工具、教学、优秀导师和优秀同事的进步，所有这些都有助于使科学事业不断引人注目。
相似文献
1
Science stories: flies, planes, worms, and lasers.科学故事：苍蝇、飞机、蠕虫和激光。
Mol Biol Cell. 2011 Nov;22(21):3921-2. doi: 10.1091/mbc.E11-05-0450.
2
Spatial and temporal impacts on a career in science.科学职业的时空影响。
Mol Biol Cell. 2011 Nov;22(21):3923-5. doi: 10.1091/mbc.E11-05-0446.
3
From junior to senior: advice from the benefit of 20/20 hindsight.从初出茅庐到资深人士：基于事后诸葛亮的建议。
Mol Biol Cell. 2014 Nov 1;25(21):3259-62. doi: 10.1091/mbc.E14-06-1081.
4
My winding trail while fulfilling my love for science and family.我在追求对科学和家庭的热爱的道路上曲折前行。
J Biol Chem. 2018 Jul 6;293(27):10435-10437. doi: 10.1074/jbc.AW118.003225. Epub 2018 Apr 11.
5
A tale of mother and daughter.一个关于母亲和女儿的故事。
Mol Biol Cell. 2010 Jan 1;21(1):7-8. doi: 10.1091/mbc.e09-08-0658.
6
A career at the interface of cell and developmental biology: a view from the crest.细胞与发育生物学交叉领域的职业生涯：来自嵴的观点。
Mol Biol Cell. 2012 Nov;23(21):4151-3. doi: 10.1091/mbc.E12-05-0389.
7
The joy of a career in cell biology.细胞生物学职业的乐趣。
Mol Biol Cell. 2010 Nov 15;21(22):3764-6. doi: 10.1091/mbc.E10-05-0413.
8
Bob Goldstein: cell biology by way of development. Interviewed by Caitlin Sedwick.鲍勃·戈德斯坦：从发育生物学角度研究细胞生物学。凯特琳·塞德威克采访。
J Cell Biol. 2013 Aug 5;202(3):400-1. doi: 10.1083/jcb.2023pi.
9
A different kind of quarterback.一种不同类型的四分卫。
Mol Biol Cell. 2011 Nov;22(21):3926-8. doi: 10.1091/mbc.E11-05-0471.
10
2009 winner: Ravi Desai.2009年获奖者：拉维·德赛。
J Cell Sci. 2010 Mar 15;123(Pt 6):815. doi: 10.1242/jcs.069278.
引用本文的文献
1
Moving from trainee to junior: faculty: a brief guide.从实习生到初级医生：教员：简要指南。
Physiologist. 2014 Jan;57(1):3-6.
本文引用的文献
1
Global up-regulation of microtubule dynamics and polarity reversal during regeneration of an axon from a dendrite.在树突再生为轴突的过程中，微管动力学和极性的全局上调。
Mol Biol Cell. 2010 Mar 1;21(5):767-77. doi: 10.1091/mbc.e09-11-0967. Epub 2010 Jan 6.
2
Microtubules have opposite orientation in axons and dendrites of Drosophila neurons.微管在果蝇神经元的轴突和树突中具有相反的方向。
Mol Biol Cell. 2008 Oct;19(10):4122-9. doi: 10.1091/mbc.e07-10-1079. Epub 2008 Jul 30.
3
Caenorhabditis elegans neuronal regeneration is influenced by life stage, ephrin signaling, and synaptic branching.秀丽隐杆线虫的神经元再生受生命阶段、 Ephrin 信号传导和突触分支的影响。
Proc Natl Acad Sci U S A. 2007 Sep 18;104(38):15132-7. doi: 10.1073/pnas.0707001104. Epub 2007 Sep 11.
4
Polarity and intracellular compartmentalization of Drosophila neurons.果蝇神经元的极性和细胞内区室化
Neural Dev. 2007 Apr 30;2:7. doi: 10.1186/1749-8104-2-7.
5
Formation of microtubule-based traps controls the sorting and concentration of vesicles to restricted sites of regenerating neurons after axotomy.基于微管的陷阱的形成控制着轴突切断后囊泡向再生神经元受限部位的分选和聚集。
J Cell Biol. 2007 Feb 12;176(4):497-507. doi: 10.1083/jcb.200607098. Epub 2007 Feb 5.
6
Controlled damage in thick specimens by multiphoton excitation.通过多光子激发对厚样本进行可控损伤。
Mol Biol Cell. 2003 May;14(5):1808-17. doi: 10.1091/mbc.e02-03-0163. Epub 2003 Jan 26.
7
Targeting of rough endoplasmic reticulum membrane proteins and ribosomes in invertebrate neurons.无脊椎动物神经元中粗面内质网膜蛋白和核糖体的靶向作用。
Mol Biol Cell. 2002 May;13(5):1778-91. doi: 10.1091/mbc.01-10-0514.
8
A visual screen of a GFP-fusion library identifies a new type of nuclear envelope membrane protein.对绿色荧光蛋白（GFP）融合文库进行可视化筛选，鉴定出一种新型核被膜蛋白。
J Cell Biol. 1999 Jul 12;146(1):29-44. doi: 10.1083/jcb.146.1.29.
9
Polarity orientation of microtubules in hippocampal neurons: uniformity in the axon and nonuniformity in the dendrite.海马神经元中微管的极性取向：轴突中的一致性和树突中的不一致性。
Proc Natl Acad Sci U S A. 1988 Nov;85(21):8335-9. doi: 10.1073/pnas.85.21.8335.
Zotero 插件