当前具有抗肿瘤潜力的铂类配合物中的非经典结构。

Non-classical structures among current platinum complexes with potential as antitumor drugs.

机构信息

Departamento de Quimica Inorgánica, Universidad Autónoma de Madrid, C7 Francisco Tomás y Valiente, 7.28049 Madrid, Spain.

出版信息

Curr Top Med Chem. 2011;11(21):2613-22. doi: 10.2174/156802611798040723.

DOI:10.2174/156802611798040723

PMID:22039872

Abstract

The potential and limitations of the non classical metallodrugs with platinum as metal are discussed in this section, focusing not only in their design but in their mechanism of action and interaction with other biomolecules to introduce and encourage the readers on the potential of this field.

摘要

本节讨论了以铂为金属的非经典金属药物的潜力和局限性，不仅关注其设计，还关注其作用机制以及与其他生物分子的相互作用，旨在向读者介绍和鼓励该领域的潜力。