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[IT-Knife-2 电切术作为吻合口狭窄的主要治疗方法]

[IT-Knife-2 electroincision as primary treatment of anastomotic strictures].

作者信息

Alonso-Lárraga J O, Reyes-Bastidas M R, Sobrino-Cossio S, Hernández-Guerrero A, López-Alvarenga J C

机构信息

Adscrito al Servicio Endoscopia Digestiva, Instituto Nacional de Cancerología, SSA, México, D F.

出版信息

Rev Gastroenterol Mex. 2011 Jul-Sep;76(3):217-23.

Abstract

BACKGROUND

Dysphagia is a common problem after surgical stenosis (5% to 55%) and can be refractory to conventional endoscopic treatment in 22% of cases. It has been proposed that electro-incision is an alternative and effective treatment.

OBJECTIVE

To evaluate the effectiveness of electro-incision with the insulation-tipped diathermic Knife-2 (IT-Knife-2) in the treatment of dysphagia produced by surgical anastomotic strictures.

METHODS

Longitudinal and case-series study from August 2009 to June 2010. Eight consecutive patients with anastomotic stricture-associated dysphagia and naive to endoscopic treatment were included. We performed three or more radiated cuts in the stricture until passage of the gastroscope was achieved with IT-Knife-2 and electrocautery (ERBE IC 200) with a 70-100 W energy cut-off and 25 W coagulation. We carried out measurements at baseline and 15 days after the intervention, evaluating the dysphagia by the Atkinson grading scale and endoscopic changes.

RESULTS

The majority of patients were at clinical stage IV with an Eastern Cooperative Oncology Group score of 1 - 3 and Karnofsky between 40 and 90. At the time of endoscopic diagnosis, patients had dysphagia grade II and III. Strictures in all of the cases were short in length and had a diameter of minor than 5 mm. At 15 days of the intervention, no patient demonstrated dysphagia (p = 0.0013) and the anastomotic diameters was more than 9.5 mm and without evidence of stenosis (p = 0.0001). None of our patients presented postincisional complications.

CONCLUSIONS

Electro-incision with IT-Knife-2 is effective as primary treatment for the relief of benign dysphagia associated with postsurgical anastomotic stenosis."

摘要

背景

吞咽困难是手术狭窄后常见的问题(发生率为5%至55%),在22%的病例中对传统内镜治疗无效。有人提出电切术是一种替代且有效的治疗方法。

目的

评估使用绝缘头电热刀-2(IT-Knife-2)进行电切术治疗手术吻合口狭窄所致吞咽困难的有效性。

方法

2009年8月至2010年6月的纵向病例系列研究。纳入8例连续的吻合口狭窄相关吞咽困难且未接受过内镜治疗的患者。我们使用IT-Knife-2和电灼器(ERBE IC 200)在狭窄部位进行三次或更多次放射状切割,能量截止为70 - 100 W,凝固功率为25 W,直至胃镜能够通过。在基线和干预后15天进行测量,通过阿特金森分级量表评估吞咽困难情况,并观察内镜下变化。

结果

大多数患者处于临床IV期,东部肿瘤协作组评分为1 - 3分,卡氏评分在40至90之间。在内镜诊断时,患者吞咽困难分级为II级和III级。所有病例的狭窄长度较短,直径小于5 mm。干预后15天,无患者出现吞咽困难(p = 0.0013),吻合口直径大于9.5 mm且无狭窄迹象(p = 0.0001)。我们的患者均未出现术后并发症。

结论

使用IT-Knife-2进行电切术作为缓解与手术后吻合口狭窄相关的良性吞咽困难的初始治疗方法是有效的。

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