Otsuka Kengo, Kuronuma Koji, Otsuka Mitsuo, Kitada Junya, Narita Yoshifumi, Homma Hirotoshi, Miyajima Satsuki, Kitamura Yasuo, Suzuki Yosuke, Natsuizaka Motoki, Yasui Hiroshi, Ikeda Hiroshi, Hayashi Toshiaki, Ishida Tadao, Shinomura Yasuhisa, Noguchi Hiroko, Takahashi Hiroki
The Third Department of Internal Medicine, Sapporo Medical University School of Medicine, Japan.
Intern Med. 2011;50(21):2637-41. doi: 10.2169/internalmedicine.50.5930. Epub 2011 Nov 1.
A 57-year-old woman was referred to our hospital for further examination of a tracheal stenosis shown on computed tomography findings. Bronchoscopy revealed multiple protruding tumors in the lumen of the trachea. Cytological findings of the cell block material from pleural effusion indicated that the T-cell lymphoma was composed of pleomorphic lymphoid cells. Serum human T-cell leukemia virus type 1 antibody was positive and supported the clinical diagnosis of ATLL. Systemic chemotherapy induced the remarkable improvement of the lesions, the infiltrative lung shadow and the soft tissue neoplasm. We report a rare case of adult T cell leukemia/lymphoma (ATLL) with endobronchial involvement.
一名57岁女性因计算机断层扫描发现气管狭窄而被转诊至我院进一步检查。支气管镜检查显示气管腔内有多个突出肿瘤。胸腔积液细胞块材料的细胞学检查结果表明,T细胞淋巴瘤由多形性淋巴细胞组成。血清人类T细胞白血病病毒1型抗体呈阳性,支持成人T细胞白血病/淋巴瘤(ATLL)的临床诊断。全身化疗使病变、浸润性肺部阴影和软组织肿瘤明显改善。我们报告了一例罕见的成人T细胞白血病/淋巴瘤(ATLL)累及支气管内的病例。