Matsumoto Yoshinori, Wakabayashi Hiroshi, Otsuka Fumio, Inoue Kentaro, Takano Mariko, Sada Ken-ei, Makino Hirofumi
Department of Medicine and Clinical Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Japan.
Intern Med. 2011;50(21):2669-73. doi: 10.2169/internalmedicine.50.5966. Epub 2011 Nov 1.
Acute myocardial infarction (AMI) is one of the most severe manifestations in patients with systemic lupus erythematosus (SLE). Ischemic colitis, mainly caused by intestinal vasculitis, is also one of the most serious, but uncommon, complications in SLE patients. "SLE vasculitis" simultaneously involving cardiac and gastrointestinal vessels has yet to be reported. This is the first report of SLE accompanying AMI, ischemic colitis and perforation of the digestive tract possibly due to SLE vasculitis, which was dramatically improved by treatment with high-dose glucocorticoid.
急性心肌梗死(AMI)是系统性红斑狼疮(SLE)患者最严重的表现之一。缺血性结肠炎主要由肠道血管炎引起,也是SLE患者最严重但不常见的并发症之一。“SLE血管炎”同时累及心脏和胃肠道血管的情况尚未见报道。本文首次报告了SLE伴发AMI、缺血性结肠炎及消化道穿孔,可能系SLE血管炎所致,经大剂量糖皮质激素治疗后病情显著改善。