McGouran D C R, Petterson T, McLaren J M, Wolbinski M P
Department of Medicine, Hutt Valley Hospital, Lower Hutt, New Zealand.
Acute Med. 2011;10(2):81-2.
The Stevens-Johnson syndrome (SJS) classically involves a rash, conjunctivitis and mucositis. We describe the case of a young adult male with isolated mucositis and conjunctivitis . Previous rare reports of severe SJS like syndromes without a rash are confined to children, usually with mycoplasma pnemoniae infection.(1) Terminology for this syndrome includes - "Stevens-Johnson Syndrome without skin lesions", or "Atypical Stevens - Johnson Syndrome".(2) This case highlights the importance of maintaining an open mind when a "full house" of clinical features is absent. It also illustrates the use of a rapid electronic literature review as a clinical tool. The importance of updating records when a drug has been cleared of causing harm is highlighted.
史蒂文斯-约翰逊综合征(SJS)典型表现为皮疹、结膜炎和黏膜炎。我们报告一例仅出现黏膜炎和结膜炎的年轻成年男性病例。既往关于无皮疹的严重SJS样综合征的罕见报道仅限于儿童,通常与肺炎支原体感染有关。(1)该综合征的术语包括——“无皮肤损害的史蒂文斯-约翰逊综合征”或“非典型史蒂文斯-约翰逊综合征”。(2)该病例凸显了在缺乏“完整”临床特征时保持开放思维的重要性。它还说明了使用快速电子文献综述作为临床工具的情况。强调了在药物已被排除造成危害时更新记录的重要性。