[医学微生物学中毒素 - 抗毒素理论的问题史]
[The problem history of the toxin-antitoxin theory in medical microbiology].
作者信息
Opitz B
机构信息
Evangelisches Krankenhaus Paul-Gerhardt-Stift.
出版信息
Z Gesamte Hyg. 1990 Jul;36(7):378-80.
PMID:2204237
Abstract
The paper presents the history of the toxin-antitoxin theory. It covers the working hypotheses of the pathological-anatomical and clinical research (Virchow and Oertel), the experimental evidence of the diphtheria toxin by Roux and Yersin, up to the discovery of the antitoxin effect by Behring. The differences between an experimental based theory and the speculative conceptions of that time are discussed.
摘要
本文介绍了毒素-抗毒素理论的历史。它涵盖了病理解剖学和临床研究的工作假设（魏尔啸和厄特尔）、鲁和耶尔森对白喉毒素的实验证据，直至贝林发现抗毒素效应。文中还讨论了基于实验的理论与当时的推测性概念之间的差异。
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