Gurguis G N, Uhde T W
Section on Anxiety and Affective Disorders, National Institute of Mental Health, Bethesda, MD 20892.
Biol Psychiatry. 1990 Aug 15;28(4):292-6. doi: 10.1016/0006-3223(90)90656-m.
The effects of oral yohimbine (20 mg) or placebo or both drugs on plasma homovanillic acid (HVA) were evaluated in patients with panic disorder and normal controls. Panic disorder patients had similar HVA values at baseline compared with normal controls, and yohimbine failed to produce appreciable changes in HVA in both groups. These findings are discussed within the context of catecholaminergic theories of panic disorder.
在惊恐障碍患者和正常对照中评估了口服育亨宾（20毫克）、安慰剂或两种药物对血浆高香草酸（HVA）的影响。惊恐障碍患者在基线时的HVA值与正常对照相似，育亨宾未能使两组的HVA产生明显变化。在惊恐障碍的儿茶酚胺能理论背景下对这些发现进行了讨论。
