异常锥体束与人类大脑锥体束的特征比较。

Characteristics of the aberrant pyramidal tract in comparison with the pyramidal tract in the human brain.

机构信息

Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University, Daegu, Republic of Korea.

出版信息

BMC Neurosci. 2011 Nov 1;12:108. doi: 10.1186/1471-2202-12-108.

DOI:10.1186/1471-2202-12-108

PMID:22044747

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3217915/

Abstract

BACKGROUND

The aberrant pyramidal tract (APT) refers to the collateral pathway of the pyramidal tract (PT) through the medial lemniscus in the midbrain and pons. Using diffusion tensor tractography (DTT), we investigated the characteristics of the APT in comparison with the PT in the normal human brain.

RESULTS

In thirty-four (18.3%, right hemisphere: 20, left hemisphere: 14) of the 186 hemispheres, the APTs separated from the PT at the upper midbrain level, descended through the medial lemniscus from the midbrain to the pons, and then rejoined with the PT at the upper medulla. Nine (26.5%) of the 34 APTs were found to originate from the primary somatosensory cortex without a primary motor cortex origin. Values of fractional anisotropy (FA) and tract volume of the APT were lower than those of the PT (P < 0.05); however, no difference in mean diffusivity (MD) value was observed (P > 0.05).

CONCLUSION

We found that the APT has different characteristics, including less directionality, fewer neural fibers, and less origin from the primary motor cortex than the PT.

摘要

背景

异常的锥体束（APT）是指锥体束（PT）通过中脑和脑桥的内侧丘系的侧支通路。使用弥散张量纤维束成像（DTT），我们研究了 APT 在正常人类大脑中的特征，与 PT 进行了比较。

结果

在 186 个半脑中，有 34 个（18.3%，右半球：20，左半球：14）的 APT 在上中脑水平与 PT 分离，从中脑向下通过内侧丘系下降到脑桥，然后在延髓上部与 PT 重新结合。在 34 个 APT 中，有 9 个（26.5%）起源于初级体感皮层，而不是初级运动皮层。APT 的各向异性分数（FA）和束体积值均低于 PT（P<0.05）；然而，平均弥散度（MD）值没有差异（P>0.05）。