Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA.
Neurocrit Care. 2013 Feb;18(1):93-5. doi: 10.1007/s12028-011-9646-0.
Uterine leiomyoma (or fibroid) can be associated with secondary polycythemia and venous thrombosis, but there has been no report of intracranial venous thrombosis associated with leiomyoma.
We describe a case report of a cerebral venous thrombosis associated with erythrocytosis and a uterine fibroid in a non-smoking female with no history of malignancy or hormone use. The hemoglobin and erythropoietin normalized after removal of her uterine fibroid.
MRI/MRV of this 60-year-old cephalalgic female revealed extensive thrombus throughout the sagittal sinus and right transverse sinus. CT of the abdomen revealed a 16 × 13 × 12 cm solid mass arising for the uterus consistent with a uterine fibroid. PET scan was negative for malignancy. Hemoglobin on admission was 18.4 g/dl. Erythropoietin was 16.6 mIU/ml. One month after hysterectomy, her hemoglobin was 12.6 g/dl and her erythropoietin was 4.7 mIU/ml.
Cerebral vein thrombosis is a potential complication of uterine fibroids with erythrocytosis.
子宫肌瘤（或纤维瘤）可伴发继发性红细胞增多症和静脉血栓形成，但尚未有报道称子宫肌瘤会引起颅内静脉血栓形成。
我们描述了一例非吸烟女性因子宫肌瘤伴红细胞增多症和颅内静脉血栓形成的病例报告。该女性无恶性肿瘤或激素使用史。子宫肌瘤切除后，血红蛋白和促红细胞生成素恢复正常。
这名 60 岁头痛女性的 MRI/MRV 显示矢状窦和右侧横窦内广泛血栓形成。腹部 CT 显示起源于子宫的 16×13×12 cm 实性肿块，符合子宫肌瘤。PET 扫描未发现恶性肿瘤。入院时血红蛋白为 18.4 g/dl，促红细胞生成素为 16.6 mIU/ml。子宫切除术后 1 个月，血红蛋白为 12.6 g/dl，促红细胞生成素为 4.7 mIU/ml。
子宫肌瘤伴红细胞增多症可引起脑静脉血栓形成，这是一种潜在的并发症。
