Riddle M C
Division of Endocrinology/Diabetes/Clinical Nutrition, Oregon Health Sciences University, Portland.
Geriatrics. 1990 Sep;45(9):32-6.
Diabetic neuropathy is a common, varied, and disabling disease that is potentially responsive to therapy. While its pathogenesis is as yet unclear, its clinical presentations and natural history are well known. Present information suggests glycemic control can prevent neuropathy and in some cases cause established neuropathy to regress. Drug therapy is useful only for painful neuropathy. Avoidance of alcohol and behavioral and surgical relief of nerve entrapment are helpful in certain cases.
糖尿病性神经病变是一种常见、多样且致残的疾病,可能对治疗有反应。虽然其发病机制尚不清楚,但其临床表现和自然病程是众所周知的。目前的信息表明,血糖控制可以预防神经病变,在某些情况下还可使已有的神经病变消退。药物治疗仅对疼痛性神经病变有效。在某些情况下,避免饮酒以及通过行为和手术缓解神经受压会有所帮助。