Gabelman C, Al-Sadir J, Lamberti J, Fozzard H A, Laufer E, Replogle R L, Myerowitz P D
J Thorac Cardiovasc Surg. 1979 Jun;77(6):914-21.
A young woman presented with a tumor in the left atrium resembling a left atrial myxoma. After simple excision of the tumor the diagnosis of primary malignant fibrous histiocytoma of the heart was made. A course of radiation therapy was given. Four subsequent recurrences were treated by cardiotomy and resection of the left atrial wall. At the third, fourth, and fifth operations fulguration of the left atrial wall was performed. Subsequent chemotherapy failed to control the tumor. The patient was admitted 6 weeks after the last resection and died. Postmortem examination revealed a large recurrent tumor obstructing the left atrium with no metastases. The clinical course, cardiac catherization data, and postmortem examination are presented. Palliation was achieved by repeated resection of a radiation-resistent primary sarcoma of the heart.
一名年轻女性因左心房出现类似左心房黏液瘤的肿瘤前来就诊。肿瘤简单切除后，确诊为原发性心脏恶性纤维组织细胞瘤。进行了一个疗程的放射治疗。随后又有四次复发，均通过心脏切开术和左心房壁切除术进行治疗。在第三次、第四次和第五次手术中，对左心房壁进行了电灼。随后的化疗未能控制肿瘤。患者在最后一次切除术后6周入院并死亡。尸检发现一个大的复发性肿瘤阻塞左心房，无转移。本文介绍了临床病程、心导管检查数据和尸检情况。通过反复切除抗辐射的原发性心脏肉瘤实现了姑息治疗。
