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[肿瘤溶解综合征:病例报告及文献综述]

[The tumor lysis syndrome: case report and review of the literature].

作者信息

Galesić K, Sabljar-Matovinović M, Morović-Vergles J, Minigo H, Jaksić B

机构信息

Klinicka bolnica Dr. Ozren Novosel, Klinika za unutarnje bolesti, Zagreb.

出版信息

Lijec Vjesn. 1990 Mar-Apr;112(3-4):99-102.

PMID:2204777
Abstract

Tumor lysis syndrome is specific acute renal failure. This syndrome is usually a complication of cytostatic therapy in patients with acute lymphoblastic leukemia and lymphoblastic lymphoma. Tumor cell lysis following chemotherapy may lead to metabolic complications and renal failure. We report herein, two patients with acute lymphoblastic leukemia who developed tumor lysis syndrome after chemotherapy. Furthermore, we describe important measures to prevent tumor lysis syndrome in high risk patients.

摘要

肿瘤溶解综合征是一种特殊的急性肾衰竭。该综合征通常是急性淋巴细胞白血病和淋巴细胞淋巴瘤患者接受细胞毒性治疗后的并发症。化疗后肿瘤细胞溶解可能导致代谢并发症和肾衰竭。我们在此报告两名急性淋巴细胞白血病患者,他们在化疗后发生了肿瘤溶解综合征。此外,我们描述了在高危患者中预防肿瘤溶解综合征的重要措施。

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