Richeson R B, Stander P E
University of California, Davis, Medical Center, Sacramento.
Postgrad Med. 1990 Sep 1;88(3):217-9, 222, 224. doi: 10.1080/00325481.1990.11704739.
Allergic bronchopulmonary aspergillosis (ABPA), an immunologic disorder, is characterized by bronchial colonization with Aspergillus species, resulting in chronic antigenic stimulation. Hallmarks of the disorder are asthma, cutaneous and serologic evidence of hypersensitivity to Aspergillus organisms, and fleeting pulmonary infiltrates. Diagnosis requires a high index of suspicion. Early diagnosis, aggressive therapy, and serial monitoring of serum IgE levels usually prevent progression of ABPA to bronchiectasis, pulmonary fibrosis, respiratory failure, and death.
变应性支气管肺曲霉病(ABPA)是一种免疫紊乱疾病,其特征为支气管被曲霉菌种定植,导致慢性抗原刺激。该疾病的特点是哮喘、对曲霉菌生物体过敏的皮肤和血清学证据,以及短暂性肺部浸润。诊断需要高度的怀疑指数。早期诊断、积极治疗以及对血清IgE水平的连续监测通常可防止ABPA进展为支气管扩张、肺纤维化、呼吸衰竭和死亡。