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系统评价自闭症谱系障碍患者的脊骨神经医学治疗文献。

A systematic review of the literature on the chiropractic care of patients with autism spectrum disorder.

机构信息

International Chiropractic Pediatric Association, Media, PA, USA.

出版信息

Explore (NY). 2011 Nov-Dec;7(6):384-90. doi: 10.1016/j.explore.2011.08.001.

Abstract

BACKGROUND

In addition to impacting the affected child and his/her family's quality of life, recent estimates place the lifetime cost for an individual with ASD at $3.2 million and $35 billion for the entire birth cohort. Given the clinical heterogeneity of ASD, treatment approaches are multidisciplinary including alternative therapies, particularly when no pharmaceutical agent is effective for the core symptoms of ASD. Chiropractic is a popular alternative therapy for children. A systematic review of the literature was performed to provide context for future research endeavors in this field.

METHODS

A systematic review of the literature on the chiropractic care of patients with ASD utilized 8 databases. Eligibility criteria for inclusion included: (1) the study was a primary investigation/report published in an English peer-reviewed journal; (2) the study involved patients ≤18 years; and (3) patients are diagnosed with autism, Asperger's Syndrome, PDD-NOS, or ASD.

RESULTS

Our systematic review of the literature revealed a total of five articles consisting of three case reports, one cohort study and one randomized comparison trial. The literature is lacking on documenting the chiropractic care of children with ASD.

DISCUSSION

At the heart of the core symptoms of ASD (ie, impaired social interactions, deficits in communication and repetitive or restricted behavioral patterns) is abnormal sensory processing. Preliminary studies indicate that the chiropractic adjustment may attenuate sensorimotor integration based on somatosensory evoked potentials studies.

CONCLUSION

We encourage further research for definitive studies on chiropractic's effectiveness for ASD. However, given the ineffectiveness of pharmaceutical agents, a trial of chiropractic care for sufferers of autism is prudent and warranted.

摘要

背景

除了影响受影响的儿童及其家庭的生活质量外,最近的估计表明,个体患有 ASD 的终生成本为 320 万美元,整个出生队列的成本为 350 亿美元。鉴于 ASD 的临床异质性,治疗方法是多学科的,包括替代疗法,特别是当没有药物制剂对 ASD 的核心症状有效时。整脊是一种受欢迎的儿童替代疗法。对 ASD 患者的脊骨疗法进行了系统的文献回顾,为该领域的未来研究提供了背景。

方法

对涉及 ASD 患者脊骨护理的文献进行了系统的文献回顾,使用了 8 个数据库。纳入标准包括:(1)研究是在英语同行评审期刊上发表的主要调查/报告;(2)研究涉及≤18 岁的患者;(3)患者被诊断为自闭症、阿斯伯格综合征、未分类的广泛性发育障碍或 ASD。

结果

我们对文献的系统回顾共发现了五篇文章,包括三篇病例报告、一篇队列研究和一篇随机对照试验。文献缺乏对记录儿童 ASD 脊骨护理的记载。

讨论

在 ASD 的核心症状(即社交互动受损、沟通和重复或受限的行为模式缺陷)的核心,是异常的感觉处理。初步研究表明,基于体感诱发电位研究,脊骨调整可能会减轻感觉运动整合。

结论

我们鼓励对脊骨疗法对 ASD 的有效性进行进一步的研究。然而,鉴于药物制剂的无效性,对自闭症患者进行脊骨护理的试验是谨慎和必要的。

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