Kinne D W
Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10021.
Cancer. 1990 Sep 15;66(6 Suppl):1373-7. doi: 10.1002/1097-0142(19900915)66:14+<1373::aid-cncr2820661412>3.0.co;2-0.
Patients with Stage I or II breast cancer are candidates for either modified radical mastectomy or breast preservation, with limited resection of the primary, axillary dissection, and breast irradiation. Overall survival rates with these two approaches are comparable in retrospective reviews and in ongoing clinical trials. Longer follow-up has confirmed earlier findings. Patients should be given these options by surgeons, radiation therapists, and other physicians involved in their care. Not all breast cancer patients will choose breast preservation, and not all are candidates for it due to tumor-related and other factors. Patient selection criteria are discussed, and optimal surgical techniques are reviewed.
I期或II期乳腺癌患者适合进行改良根治性乳房切除术或保乳手术，包括对原发灶进行有限切除、腋窝淋巴结清扫及乳房放疗。回顾性研究和正在进行的临床试验表明，这两种治疗方法的总生存率相当。更长时间的随访证实了早期的研究结果。外科医生、放疗科医生及参与患者治疗的其他医生应向患者提供这些选择。并非所有乳腺癌患者都会选择保乳手术，由于肿瘤相关因素和其他因素，也并非所有患者都适合保乳手术。本文讨论了患者的选择标准，并回顾了最佳手术技术。
